COSMETIC

• • Toxicological evaluation of cosmetic ingredients and products according to EU guidance and legislation and Scientific Committee on Consumer Safety (SCCS) guidance Risk assessment of the final products

• • Risk assessment for systemic effects of cosmetic ingredients, from experimental data, in silico predictions and read across from analogues

• • Support in qualitative assessment of local effects of cosmetic ingredients and products

• • Risk assessment of cosmetic products containing nanoparticles

• • Preparation of the Weight of Evidence to define possible Classification and Labelling

• • Impurity Safety Assessment, Genotoxicity, Toxicity and Risk Assessment

• • Identification of the critical parts of the formulation

• • Supporting Regulatory Affairs and Quality Experts (RA & QC) professionals in developing the study plan with non-animal alternative method selection (in silico and in vitro) complying with the restrictions on animal testing placed under Regulation (EC) No 1223/2009

• • Assessment to identify endocrine disruptors

• • Review of present or coming restriction / classification from the regulatory agencies

• • Hypoallergenic claim according to the technical document, experimental result and weight of evidence

• • Derivation of the sensitization potential for new cosmetic ingredient based on commercially available in silico tools (via external party)

• • Support the companies in the Development of Product Information Files (PIF) (Cosmetic Product Safety Information and Cosmetic Product Safety Assessment)

BIOTECHNOLOGICAL
SKILLS

We are experts in optimizing biological processes and in creating innovative, customized, and cutting-edge products