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OCCUPATIONAL TOXICOLOGY

S&C BEST S&C BEST

We recognize that workers especially in the chemical and pharmaceutical manufacturing industries face potential exposure to a diverse range of substances. These include active pharmaceutical ingredients, isolated pharmaceutical intermediates, and various other chemical compounds. Our team is committed to assist your company in ensuring the health and safety of your workers. We offer comprehensive services to support your organization in meeting critical requirements and, on request, in translating external guidance’s in internal procedures.

    • Toxicological evaluation of Active Pharmaceutical Ingredients (API)

 

    • Identification of the main toxicological effects and major safety concern associated with the API

 

    • Identification of eventual sub-population groups more sensible to API

 

    • Toxicokinetic assessment of the API and identification of toxicologically relevant exposure routes

 

    • Assessment of API mechanism of action and discussion over its relevance for occupational toxicology
      • PDE derivation for relevant occupational exposure routes (inhalation, dermal)

     

    • Derivation of Occupational Exposure Limit (OEL)

 

    • Identification of Occupational Exposure Band (OEB)

 

    • Derivation of Acceptable Surface Limit (ASL)

 

    • Support in cleaning validation

 

    • Assisting in the design and optimization of cleaning processes, including the selection of appropriate cleaning agents and methods

BIOTECHNOLOGICAL
SKILLS

We are experts in optimizing biological processes and in creating innovative, customized, and cutting-edge products

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